Endocrine Abstracts

Objective of our study was to investigate the renoprotective efficacy of valsartan and enalapril depending on the genetic polymorphisms of the angiotensinic system.Material and methods: In 32 type 2 diabetic patients with microalbuminuria, DNA extraction and genotypization were performed. The studied polymorphism was A1166C of the AT1-receptor gene. Two types of antiangiotensinic drugs were used in order to reduce microalbuminuria: enalapril (20 mg/d) an...

Introduction: The thyroid is a multifaced endocrine gland. By its hormones it has an effect on almost all organs of the body, metabolism and defence system too. The relationship between the thyroid hormones and the nonspecific defence system has been less studied.Aim: To study and prove whether the endogenous thyroxin (FT4) is involved in the nonspecific defence system of the organism. We followed the correlation between the FT4 and...

Introduction: In vitro adipogenesis is a two-step developmental process in which an undifferentiated mesenchymal cell differentiates into a preadipocyte, which then undergoes a secondary differentiation step to become a lipid-filled adipocyte. The triglyceride accumulation is influenced by various endogenous and exogenous factors.Methods: In an attempt to understand the antipsychotics effects on lipid accumulation duri...